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Cynaptec Pharmaceuticals

Advancing novel psychedelic-derived therapeutics for neurological disorders

ABOUT CYNAPTEC

Transforming Treatment for Chronic Cluster Headache

Cynaptec Pharmaceuticals is a 64% owned subsidiary of Lobe Sciences focused on developing next-generation psychedelic-derived therapeutics. Our lead program, L-130 (Psilocin Mucate), is being developed for the treatment of chronic cluster headache—one of the most painful and underserved neurological conditions.

Cluster headache is often called “suicide headache” due to the extreme severity of pain. Current treatments offer limited relief, creating significant unmet medical need.

LEAD PROGRAM

L-130 (Psilocin Mucate)

Indication

Chronic Cluster Headache

Development Stage

Phase 1/2a

Molecule Type

Conjugated Psilocin

L-130 is a novel conjugated psilocin compound designed to provide improved pharmacokinetic properties compared to traditional psilocybin formulations. The compound offers potential advantages including more predictable dosing, improved tolerability, and reduced psychoactive side effects while maintaining therapeutic efficacy.

Explore Our Full Pipeline

Learn about all of our development programs across Lobe Sciences subsidiaries.